Charlotte Zucker, born Charlotte Ann Lefstein on March 10, 1921, in New York City, was an American actress known for her appearances in many of her sons' films, David and Jerry Zucker. She grew up in Manhattan, where her father, Harry Lefstein, was a tailor, and her mother, Sarah (née Seiden), was a housewife.

Charlotte Zucker earned a degree in speech and theater at Brooklyn College and later moved to Milwaukee to teach English at a junior high school. She graduated from the University of Wisconsin in Madison with a master's degree.

Charlotte Zucker began her acting career in community theater productions in Florida and Shorewood, Wisconsin, and was a member of the Jewish Community Center Readers Theater-Milwaukee. She made her screen debut in "The Kentucky Fried Movie" (1977) and appeared in a total of 17 films, including "Airplane!" (1980), "Ghost" (1990), "First Knight" (1995), and "Rat Race" (2001), all directed and produced by her sons.

She also appeared at the Second Avenue Theater in New York, reading selections from Molly Picon's autobiography.

Charlotte Zucker was married to Burton Zucker, a real estate developer, from 1941 until her death in 2007. They had three children: David, Jerry, and Susan. On September 5, 2007, she passed away from cancer in Shorewood, Wisconsin, at the age of 86. She was buried at Second Home Cemetery in Greenfield, Wisconsin.