Daphne Zuniga, born Daphne Eurydice Zuniga on October 28, 1962, in San Francisco, California, is an American actress known for her roles in film and television. Her mother, Agnes A. Zuniga, is a Unitarian minister of Polish and Finnish descent, and her father, Joaquin Alberto Zuniga, was originally from Guatemala and an emeritus professor of philosophy at California State University, East Bay.

Daphne Zuniga has two sisters, Jennifer and Rosario Zuniga. In her early teens, she expressed interest in acting and attended the Young Conservatory program of the American Conservatory Theater of San Francisco. After her parents divorced, she moved with her mother and sister from Berkeley, California, to Reading, Vermont, where she spent the remainder of her teenage years.

She graduated from Woodstock Union High School in Woodstock, Vermont, in 1980, after which she returned to California and enrolled at the University of California, Los Angeles to study theater arts. After leaving college, Daphne Zuniga was close friends and roommates with fellow actress Meg Ryan. Daphne made her film debut in a supporting part in the slasher film "The Dorm That Dripped Blood" (1982) while a student at UCLA.

She was then cast in the 1984 horror film "The Initiation" (1984), opposite Vera Miles and Clu Gulager. This was followed by a lead role, opposite John Cusack, in Rob Reiner's film "The Sure Thing" (1985). In 1986, she starred as Princess Vespa in Mel Brooks' memorable cult comedy "Spaceballs" (1987), followed by a supporting part in the science fiction horror sequel "The Fly II" (1989).

From 1992 to 1996, she portrayed Jo Reynolds on the wildly popular soap opera "Melrose Place" (1992), which garnered her wider mainstream exposure. Her role on the series was followed by numerous appearances on television series, including a lead role as Shelly Pierce on "American Dreams" (2004) from 2004 to 2005, and a recurring role on the popular CW series "One Tree Hill" (2003), as Victoria Davis, a role which she played from 2008 until 2012.

Daphne Zuniga married her boyfriend of 12 years, Beau David Mleczko, at Oleana Restaurant in Cambridge, Massachusetts, in June 2019. The couple, who were initially set up on a blind date 12 years ago, got engaged after a decade.