Florencia Lozano was born on December 16, 1969, in Princeton, New Jersey, to Eduardo, an architect, and Elizabeth, a Spanish teacher from Argentina. She grew up in Newton Centre, Massachusetts, and initially attended Cornell University before transferring to Brown University, where she earned her Bachelor of Arts.

She later moved to New York City to pursue a Master of Fine Arts degree at New York University's Tisch School of the Arts.

Florencia Lozano is best known for her role as attorney Téa Delgado on the daytime soap opera "One Life to Live," a character that earned her a loyal following and critical acclaim. She joined the show in December 1996 and continued in the role until 2002. Her portrayal of Téa Delgado was so well-received that she was still receiving fan mail years after leaving the show.

Florencia Lozano has guest-starred in several primetime television shows, including "Law & Order: Criminal Intent," "Law & Order: Special Victims Unit," "Gossip Girl," and "Lipstick Jungle." She has also appeared in films such as "Perfect Stranger" and "The Ministers."

Her career extends beyond television and film; she has also been involved in regional theater, performing in plays like "Yerma," "Antigone," and "Hamlet."

Florencia Lozano is currently living in New York City and is single. She describes herself as curious and is learning how to meditate. Her parents' move from Argentina to the United States provided her with many opportunities, and she is grateful for the life she has had.

Throughout her career, she has been nominated for several awards, including the National Council of La Raza's American Latino Media Arts (ALMA) Awards for Outstanding Actress in a Daytime Soap Opera. She has also won Voice Arts Awards for her performance on the Western audio drama podcast "Powder Burns."