Matthew Francis Kalil, born on July 6, 1989, in Corona, California, is a former American football offensive tackle who played in the National Football League.

Of Lebanese and Mexican descent, he grew up in a football-oriented family; his father, Frank Kalil, played college football at Arkansas and Arizona before a brief professional career, and his brother Ryan became an All-American at USC and a longtime NFL center.

Matt Kalil attended Servite High School in Anaheim, where he excelled as an offensive and defensive lineman, earning honors like Parade All-American and multiple Cal-Hi Sports All-State selections, while also competing in track and field with notable throws in shot put and discus.​

Rated a five-star recruit, Matt Kalil joined the USC Trojans in 2008, redshirting his first year before serving as a backup right tackle and seeing action in 11 games during his freshman season. 

He claimed the starting left tackle position as a sophomore in 2010, starting all 13 games and contributing on special teams, including blocking a point-after against Notre Dame.

In his junior year of 2011, Matt Kalil anchored an elite offensive line that allowed just eight sacks league-wide, earning All-American recognition, the Morris Trophy as Pac-12's top lineman, and a Lombardi Award semifinalist nod, prompting his early entry into the 2012 NFL Draft.​

Regarded as the premier offensive tackle prospect, Matt Kalil impressed at the NFL Combine with measurements of 6 ft 6⅝ in, 306 lb, a 5.13-second 40-yard dash, and 30 bench press reps, leading the Minnesota Vikings to select him fourth overall after a draft-day trade, their first first-round offensive lineman since 2002.

He signed a four-year deal and started all 16 games as a rookie in 2012, earning PFWA All-Rookie honors and a Pro Bowl alternate spot, while facing his brother Ryan in a 2013 Vikings-Panthers matchup where their sister Danielle sang the national anthem.

Matt Kalil started 64 games over five Vikings seasons but battled injuries, including a 2016 hip issue that sidelined him.​

In March 2017, he joined the Carolina Panthers on a five-year, $55 million contract, reuniting with Ryan as the first brothers on the same NFL offensive line in 24 years, and he started all 16 games that season.

Injuries persisted, with a 2018 knee procedure landing him on injured reserve, leading to his release in March 2019 after earning over $57 million in his career. He briefly signed with the Houston Texans that spring but was cut before the season, effectively retiring from professional football thereafter.​

Matt Kalil married model Haley Baylee O'Brien in Hawaii on July 8, 2015, renewing vows the next year before their 2022 divorce; he wed model Keilani Asmus in Las Vegas on April 13, 2024.

Standing 6 ft 7 in and weighing 308 lb during his career, he appeared in minor acting roles on shows like "The League" and "Hello Tomorrow!" while accumulating modest defensive stats over 82 NFL games, including three tackles and one fumble recovery.​