Wendy Raquel Robinson was born on July 25, 1967, in Los Angeles, California, and is of African-American and Native American descent. She attended Howard University, where she graduated cum laude with a Bachelor of Fine Arts in drama.

Wendy Raquel Robinson made her acting debut in 1993 on an episode of Martin and guest-starred on episodes of Thea and The Sinbad Show that same year. From 1995 to 1996, she co-starred on the short-lived NBC sitcom Minor Adjustments, starring Rondell Sheridan.

The following year, she won the role of Regina "Piggy" Grier in The WB sitcom The Steve Harvey Show, which aired for six seasons. After the series ended its run in 2002, she appeared on the short-lived sketch comedy series Cedric the Entertainer Presents with her former Steve Harvey co-star Cedric the Entertainer. She also made guest appearances on The Parkers, All of Us, and The New Adventures of Old Christine.

In 2006, Wendy Raquel Robinson began portraying the role of Tasha Mack in the comedy-drama The Game, which aired on The CW, BET, and Paramount+. The series ended in 2015 after nine seasons. She has also appeared in several films, including The Walking Dead, A Thin Line Between Love and Hate, Ringmaster, Two Can Play That Game, Rebound, Miss Congeniality, and Flatliners.

In 2014, she was cast as Cruella de Vil in Disney's Descendants. Wendy also appeared in ABC's medical drama Grey's Anatomy in 2010 and had a recurring role on the short-lived ABC comedy series The Mayor in 2017.

In 2018, she was cast in the ABC comedy-drama series Grand Hotel opposite Demián Bichir and Roselyn Sánchez. In 2022, she featured in the Netflix series Family Reunion as Joyce.

Wendy Raquel Robinson serves as the school's artistic director. Wendy was married to Marco Perkins from 2003 until their divorce in 2018. She is currently in a relationship with Michael Taylor, creator of Theatre Corner, an online video series that publishes episodes of interviews with professionals in the theatre industry.

Wendy Raquel Robinson has received three NAACP Image Award nominations for Best Actress in a Comedy for her work on The Steve Harvey Show.

Her estimated net worth is around $4 million as of 2021.